Description of theme 1
Description of theme 2
Description of theme 3
   
 

P.O. Box 9101
6500 HB, Nijmegen
The Netherlands
Geert Grooteplein 8
6525 GA, Nijmegen
The Netherlands
T +31 24 3613813
F +31 24 3618942


Otto Boerman is a full professor in radiochemistry. He heads the preclinical research group of the department of Nuclear Medicine.
Prof. dr. Otto C. Boerman

Research interests include synthesis, optimization and characterization of radiotracers for molecular imaging and molecular medicine. Radioimmunotherapy of cancer with radiolabeled antibodies and pretargeting of cancer with bispecific antibodies. Peptide receptor radionuclide targeting of cancer.
 
Recent key publications

Visser EP, Disselhorst JA, Brom M, Laverman P, Gotthardt M, Oyen WJ, Boerman OC. Spatial resolution and sensitivity of the Inveon small-animal PET scanner. J Nucl Med. 2009;50:139-147.

Vegt E, van Eerd JE, Eek A, Oyen WJ, Wetzels JF, de Jong M, Russel FG, Masereeuw R, Gotthardt M, Boerman OC. Reducing renal uptake of radiolabeled peptides using albumin fragments. J Nucl Med. 2008;49:1506-1511.

Stollman TH, Scheer MG, Leenders WP, Verrijp KC, Soede AC, Oyen WJ, Ruers TJ, Boerman OC. Specific imaging of VEGF-A expression with radiolabeled anti-VEGF monoclonal antibody. Int J Cancer. 2008;122:2310-2314.

Laverman P, Roosenburg S, Gotthardt M, Park J, Oyen WJ, de Jong M, Hellmich MR, Rutjes FP, van Delft FL, Boerman OC. Targeting of a CCK2 receptor splice variant with 111In-labelled cholecystokinin-8 (CCK8) and 111In-labelled minigastrin. Eur J Nucl Med Mol Imaging. 2008;35:386-392.

Dijkgraaf I, Kruijtzer JA, Frielink C, Corstens FH, Oyen WJ, Liskamp RM, Boerman OC. Alpha v beta 3 integrin-targeting of intraperitoneally growing tumors with a radiolabeled RGD peptide. Int J Cancer. 2007;120:605-610.