      |
|
||||||||
|
Prof. Dr. Martijn Huynen
Research interests revolve around comparative genomics and molecular biology. He investigates how to exploit the wealth of genomic information that includes complete genome data, expression data, proteomics data and protein interaction data to obtain a better understanding of the working of the cell at a molecular level. Development of both concepts and protocols to turn noisy genomics data into reliable predictions of protein function and pathways, as well using these protocols to study specific biomolecular systems, such as the mitochondria, are among his main interests. |
||||||||
|
Recent key publications Gabaldon T, Rainey D, Huynen MA. J Mol Biol. 2005 May 13;348(4):857-70. Tracing the evolution of a large protein complex in the eukaryotes, NADH:ubiquinone oxidoreductase (Complex I).
Boxma B, de Graaf RM, van der Staay GW, van Alen TA, Ricard G, Gabaldon T, van Hoek AH, Moon-van der Staay SY, Koopman WJ, van Hellemond JJ, Tielens AG, Friedrich T, Veenhuis M, Huynen MA, Hackstein JH. Related Articles, Links An anaerobic mitochondrion that produces hydrogen. Nature. 2005 Mar 3;434(7029):74-9. van Noort V, Huynen MA Combinatorial gene regulation in Plasmodium falciparum. Trends Genet. 2005 Dec 23; [Epub ahead of print] PMID: 16380193 [PubMed - as supplied by publisher] van Noort V Snel B, Huynen MA. The yeast coexpression network has a small-world, scale-free architecture and can be explained by a simple model.EMBO Rep. 2004 Mar;5(3):280-4.
|
||||||||
